Article

Self-supervised deep learning uncovers the semantic landscape of drug-induced latent mitochondrial phenotypes

2023-09-14

Abstract excerpt

<h4>SUMMARY</h4> Imaging-based high-content screening aims to identify substances that modulate cellular phenotypes. Traditional approaches screen compounds for their ability to shift disease phenotypes toward healthy phenotypes, but these end point-based screens lack an atlas-like mapping between phenotype and cell state that covers the full spectrum of possible phenotypic responses. In this study, we present Mi...

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Literature Corpus work: e832f653-5e82-561e-bfa3-ed530404f807
DOI: 10.1101/2023.09.13.557636

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