Article

JIA patient T cells differentiate into Th1, Th17 and Th1.17 effector cells under Th1 polarizing conditions

2021-10-01

Abstract excerpt

<h4>Objective</h4> T helper cells develop into discrete Th1, Th2 or Th17 lineages that selectively express IFNγ, IL-4/IL-5/IL-13, or IL-17, respectively and actively silence signature cytokines expressed by opposing lineages. Our objective was to compare Th1, Th2 and Th17 polarization in cell culture models using JIA patient samples. <h4>Methods</h4> Peripheral blood mononuclear cells were isolated from JIA or hea...

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Literature Corpus work: 26d1cd4f-eb1c-5244-a9e1-d335dc705f76
DOI: 10.1101/2021.10.01.21264425

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