Article
The effector T helper cell triade.
Rivista di biologia - 1 Jan 2000
Fietta Pieranna, Delsante Giovanni
Abstract excerpt
T lymphocytes play crucial role in immune responses. Effector T helper (Th) cells derive from progenitor naïve CD4+ T cells, after maturational process induced by antigenic stimulation. Their commitment depends on complex interactions with antigen-presenting cells in a permissive milieu, including antigenic type and load, costimulatory molecules and cytokine signaling. Committed CD4+ T cells may differentiate...
Topics
- Autoimmune Diseases
- Biomarkers
- CD4 Lymphocyte Count
- Cytokines
- Hematopoiesis
- Humans
- Hypersensitivity
- Models, Biological
- Models, Immunological
- Phenotype
- T-Lymphocytes
- T-Lymphocytes, Helper-Inducer
- T-Lymphocytes, Regulatory
- Th1 Cells
- Th2 Cells
