Article
The effector T helper cell triade.
Rivista di biologia - 1 Jan 2000
Fietta Pieranna, Delsante Giovanni
Abstract excerpt
T lymphocytes play crucial role in immune responses. Effector T helper (Th) cells derive from progenitor naïve CD4+ T cells, after maturational process induced by antigenic stimulation. Their commitment depends on complex interactions with antigen-presenting cells in a permissive milieu, including antigenic type and load, costimulatory molecules and cytokine signaling. Committed CD4+ T cells may differentiate...
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