Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TGF-β Signaling in Cellular Senescence and Aging-Related Pathology

10 Oct 2019

Abstract excerpt

Aging is broadly defined as the functional decline that occurs in all body systems. The accumulation of senescent cells is considered a hallmark of aging and thought to contribute to the aging pathologies. Transforming growth factor-β (TGF-β) is a pleiotropic cytokine that regulates a myriad of cellular processes and has important roles in embryonic development, physiological tissue homeostasis, and various...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31658594
DOI: 10.3390/ijms20205002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TGF-β Signaling in Cellular Senescence and Aging-Related PathologyPMID 31658594Read ↗

Complex Interplay Between Aging and Cancer: Role of TGF-β SignalingSemantic proximity Read ↗

TGF-β in aging and diseaseSemantic proximity Read ↗

From senescence to scarring: Exploring TGF-β signaling in cellular aging, fibrotic remodeling, and pulmonary fibrosisSemantic proximity Read ↗

TGF-β signaling in health and diseaseSemantic proximity Read ↗

TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress responseSemantic proximity Read ↗

Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexitiesSemantic proximity Read ↗

Dysfunction of TGF-β1 signaling in Alzheimer’s disease: perspectives for neuroprotectionSemantic proximity Read ↗

Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer ProgressionSemantic proximity Read ↗

Advances and Challenges in Targeting TGF-β Isoforms for Therapeutic Intervention of Cancer: A Mechanism-Based PerspectiveSemantic proximity Read ↗

Inter-organ transmission of hepatocellular senescence induces multi-organ dysfunction through the TGFβ signalling pathway.Semantic proximity Read ↗

Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseasesSemantic proximity Read ↗

Cellular Senescence in Aging, Tissue Repair, and RegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.