Article

Differential variation and expression analysis

2018-03-05

Abstract excerpt

We propose an empirical Bayes approach using a three-component mixture model, the L 2 N model, that may be applied to detect both differential expression (mean) and variation. It consists of two log-normal components ( L 2 ) for the differentially expressed (dispersed) features (one component for under-expressed [dispersed] and the other for over-expressed [dispersed] features), and a single normal component (...

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Literature Corpus work: 267a11e7-e8c8-5268-9527-049dd84bb570
DOI: 10.1101/276337

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