Article

Identification of differentially distributed gene expression and distinct sets of cancer-related genes identified by changes in mean and variability

2021-02-17

Abstract excerpt

There is increasing evidence that changes in the variability or overall distribution of gene expression are important both in normal biology and in diseases, particularly cancer. Genes whose expression differs in variability or distribution without a difference in mean are ignored by traditional differential expression-based analyses. Using a Bayesian hierarchical model that provides tests for both differential va...

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Literature Corpus work: 3c75900f-1150-574a-b97d-0c7e1bb8dfbd
DOI: 10.1101/2021.02.15.431343

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