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Article

Extracting the Strongest Signals from Omics Data: Differentially Expressed Pathways and Beyond.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Glazko Galina, Rahmatallah Yasir, Zybailov Boris, Emmert-Streib Frank

Abstract excerpt

The analysis of gene sets (in a form of functionally related genes or pathways) has become the method of choice for extracting the strongest signals from omics data. The motivation behind using gene sets instead of individual genes is two-fold. First, this approach incorporates pre-existing biological knowledge into the analysis and facilitates the interpretation of experimental results. Second, it employs a...

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Computational Biology
Computer Simulation
Data Mining
Gene Expression
Gene Expression Profiling

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Gene Regulatory Networks

Oligonucleotide Array Sequence Analysis

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PMID: 28849561
DOI: 10.1007/978-1-4939-7027-8_7
PMCID: PMC5846121

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