Article
variancePartition: interpreting drivers of variation in complex gene expression studies.
BMC bioinformatics - 25 Nov 2016
Hoffman Gabriel E, Schadt Eric E
Abstract excerpt
BACKGROUND: As large-scale studies of gene expression with multiple sources of biological and technical variation become widely adopted, characterizing these drivers of variation becomes essential to understanding disease biology and regulatory genetics. RESULTS: We describe a statistical and visualization framework, variancePartition, to prioritize drivers of variation based on a genome-wide summary, and...
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