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Article

Differential variability analysis of gene expression and its application to human diseases.

Bioinformatics (Oxford, England) - 1 Jul 2008

Ho Joshua W K, Stefani Maurizio, dos Remedios Cristobal G, Charleston Michael A

Abstract excerpt

MOTIVATION: Current microarray analyses focus on identifying sets of genes that are differentially expressed (DE) or differentially coexpressed (DC) in different biological states (e.g. diseased versus non-diseased). We observed that in many human diseases, some genes have a significant increase or decrease in expression variability (variance). As these observed changes in expression variability may be caused by...

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Identifiers

PMID: 18586739
DOI: 10.1093/bioinformatics/btn142
PMCID: PMC2718620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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