Backward translation of circular RNAs

Abstract excerpt

<title>Abstract</title> <p>Despite advancements in understanding protein synthesis, numerous eukaryotic proteins might have been overlooked and remain elusive. RNA translation, proceeding in the 5’ end-to-3’ end direction exclusively, has been recognized as the norm for nearly a century. Here, we report a novel translation mode called ‘backward translation’ (BT) of circular RNAs, in which the triplet codons of ci...

Topics

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• Gene Expression Regulation, Neoplastic
• HEK293 Cells
• HeLa Cells
• Nucleic Acid Conformation
• Protein Biosynthesis
• Receptor, Fibroblast Growth Factor, Type 1
• RNA, Circular
• Structure-Activity Relationship

Identifiers and source

Literature Corpus work

266a2234-12e5-56eb-8c0c-be98a2fd158f

DOI

10.21203/rs.3.rs-5558507/v1