CICADA: a circRNA effort to Ghost proteome

Abstract excerpt

<title>Abstract</title> <p>Coding genes constitute only a small portion of the human genome. Recently, circular RNAs (circRNAs), commonly thought to be noncoding, have been demonstrated to be translated into novel proteins, which might mediate diverse biological processes. However, it remains challenging to identify translatable circRNAs and circRNA-coded proteins. Here, we introduce CICADA, an algorithm capable...

Topics

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• Gene Expression Regulation, Neoplastic
• HEK293 Cells
• HeLa Cells
• Nucleic Acid Conformation
• Protein Biosynthesis
• Receptor, Fibroblast Growth Factor, Type 1
• RNA, Circular
• Structure-Activity Relationship

Identifiers and source

Literature Corpus work

bb4b60f4-4a87-538f-bec2-c5513bf32c81

DOI

10.21203/rs.3.rs-3326835/v1