Article
A liver slice culture-based ex vivo assay to predict the outcome of antiviral therapy for chronic hepatitis C.
Journal of viral hepatitis - 1 May 2009
Chang M-L, Sung K-F, Sheen I-S, Lin S-M, Yeh C-T
Abstract excerpt
A liver slice culture-based, ex vivo drug suppression assay was developed as a pre-therapeutic predictor for the outcome of antiviral therapy. To investigate its clinical application, 106 consecutive patients with chronic hepatitis C virus (HCV) infection were evaluated. Ex vivo drug suppression assay was performed before administrating a standard course of peginterferon plus ribavirin combination therapy....
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