Article

The second lineage differentiation of bovine embryos fails in the absence of OCT4/POU5F1

2021-09-06

Abstract excerpt

<h4>ABSTRACT</h4> The mammalian blastocyst undergoes two lineage segregations, i.e., formation of the trophectoderm and subsequently differentiation of the hypoblast (HB) from the inner cell mass, leaving the epiblast (EPI) the remaining pluripotent lineage. To clarify expression patterns of markers specific for these lineages in bovine embryos, we analyzed day 7, 9 and 12 blastocysts completely derived ex vivo...

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Literature Corpus work: 26533140-cb8f-5958-81e8-06f9d05375a0
DOI: 10.1101/2021.09.06.459107

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