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Molecular profiling of bovine primordial germ cell specification and migration onset reveals a conserved program in bilaminar disc embryos

2025-06-08

Abstract excerpt

The goal of this study was to establish the timing and location of bovine primordial germ cell (PGC) specification, as well as the molecular characteristics that differentiate early PGCs from other cells in the embryo. A founder population of PGCs was identified via protein immunolocalization in the posterior epiblast (TBXT+) region at E16, by the unique co-expression of OCT4, SOX17, PRDM1, and TFAP2C with absent...

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Literature Corpus work
ce8c67fe-e57f-589e-beb9-025b1611434e
DOI
10.1101/2025.06.04.657951
Open publication

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Molecular profiling of bovine primordial germ cell specification and migration onset reveals a conserved program in bilaminar disc embryosDOI 10.1101/2025.06.04.657951
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