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PANOGA: a web server for identification of SNP-targeted pathways from genome-wide association study data.

Bioinformatics (Oxford, England) - 1 May 2014

Bakir-Gungor Burcu, Egemen Ece, Sezerman Osman Ugur

Abstract excerpt

Genome-wide association studies (GWAS) have revolutionized the search for the variants underlying human complex diseases. However, in a typical GWAS, only a minority of the single-nucleotide polymorphisms (SNPs) with the strongest evidence of association is explained. One possible reason of complex diseases is the alterations in the activity of several biological pathways. Here we present a web server called...

Topics

Genome-Wide Association Study
Humans
Internet
Linkage Disequilibrium
Phenotype
Polymorphism, Single Nucleotide
Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24413675
DOI: 10.1093/bioinformatics/btt743

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