Article
Age-associated changes in endothelial transcriptome and chromatin landscape correlate with elevated risk of hemorrhage
2023-02-10
Abstract excerpt
Intracerebral hemorrhage (ICH), a devastating form of stroke, is a leading global cause of human death and disability. The major risk factors for ICH include increasing age, hypertension and cerebral amyloid angiopathy. Despite high mortality and morbidity associated with ICH, the mechanisms leading to blood-brain barrier (BBB) dysfunction with age and development of hemorrhagic stroke is poorly understood. In the...
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Identifiers and source
- Literature Corpus work
- 262c5755-c7b8-593b-8e07-4c3b51d17c1f
- DOI
- 10.1101/2023.02.10.528012