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Article

Age-specific transcriptional response to stroke.

Neurobiology of aging - 1 Jul 2014

Sieber Matthias W, Guenther Madlen, Jaenisch Nadine, Albrecht-Eckardt Daniela, Kohl Matthias, Witte Otto W, Frahm Christiane

Abstract excerpt

Increased age is a major risk factor for stroke incidence and post-ischemic mortality. To develop age-adjusted therapeutic interventions, a clear understanding of the complexity of age-related post-ischemic mechanisms is essential. Transient occlusion of the middle cerebral artery--a model that closely resembles human stroke--was used to induce cerebral infarction in mice of 4 different ages (2, 9, 15, 24...

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Identifiers

PMID: 24529500
DOI: 10.1016/j.neurobiolaging.2014.01.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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