Article

High-Spermidine-Producing Yeast Strain for Autophagy-Promoting Applications

2025-08-26

Abstract excerpt

Polyamines, particularly spermidine, have emerged as key dietary factors with roles in cellular health, autophagy, and longevity. However, strategies for scalable production of polyamine-rich food ingredients remain limited. Here, we report the development of a high-spermidine-producing Saccharomyces cerevisiae strain, 3L63, obtained via ultraviolet mutagenesis of the K7 strain. This strain exhibited a 5.9-fold in...

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Literature Corpus work: 2612ac49-d85f-5c70-8cab-010167d49b5c
DOI: 10.20944/preprints202508.1888.v1

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