Article
Evolutionary engineering and molecular characterization of a caffeine-resistant Saccharomyces cerevisiae strain.
World journal of microbiology & biotechnology - 14 Nov 2019
Sürmeli Yusuf, Holyavkin Can, Topaloğlu Alican, Arslan Mevlüt, Kısakesen Halil İbrahim, Çakar Zeynep Petek
Abstract excerpt
Caffeine is a naturally occurring alkaloid, where its major consumption occurs with beverages such as coffee, soft drinks and tea. Despite a variety of reports on the effects of caffeine on diverse organisms including yeast, the complex molecular basis of caffeine resistance and response has yet to be understood. In this study, a caffeine-hyperresistant and genetically stable Saccharomyces cerevisiae mutant was...
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