Article
Physiological and Transcriptomic Analysis of a Chronologically Long-Lived Saccharomyces cerevisiae Strain Obtained by Evolutionary Engineering.
Molecular biotechnology - 1 Jul 2018
Arslan Mevlüt, Holyavkin Can, Kısakesen Halil İbrahim, Topaloğlu Alican, Sürmeli Yusuf, Çakar Zeynep Petek
Abstract excerpt
High-throughput aging studies with yeast as a model organism involve transposon-mutagenesis and yeast knockout collection, which have been pivotal strategies for understanding the complex cellular aging process. In this study, a chronologically long-lived Saccharomyces cerevisiae mutant was successfully obtained by using another high-throughput approach, evolutionary engineering, based on systematic selection in...
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