Article

Enrichment of charge-absent regions in phase separated proteins

2022-11-06

Abstract excerpt

Many studies focus on the relationship between protein charge and liquid-liquid phase separation (LLPS), generally finding that a large degree of charge neutralisation is involved for condensate formation. Here, sequences within human proteins that lack the charge-bearing residues Asp, Glu, Lys, and Arg (termed charge-absent) are analysed alongside annotation for involvement in LLPS. Scaffold proteins, central to...

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Literature Corpus work: 9d9087e7-32d3-561f-bf6a-273705e3fdcd
DOI: 10.1101/2022.11.05.515309

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