Article

Rise of oligodendroglioma hypermutator phenotype from a subclone harboring TP53 mutation after TMZ treatment

2023-09-29

Abstract excerpt

<title>Abstract</title> <p>Oligodendrogliomas characterized and defined by 1p/19q co-deletion are slowly glowing tumors showing better prognosis than astrocytomas. <italic>TP53</italic> mutation is rare in oligodendrogliomas while the vast majority of astrocytomas harbor the mutation, making <italic>TP53</italic> mutation mutually exclusive with 1p/19q codeletion in lower grade gliomas virtually. We report a case...

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Identifiers and source

Literature Corpus work: 25eaadd9-d3b4-5829-beee-126c34ade1e1
DOI: 10.21203/rs.3.rs-3331431/v1

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