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Article

Genetic and epigenetic stability of oligodendrogliomas at recurrence.

Acta neuropathologica communications - 7 Mar 2017

Aihara Koki, Mukasa Akitake, Nagae Genta, Nomura Masashi, Yamamoto Shogo, Ueda Hiroki, Tatsuno Kenji, Shibahara Junji, Takahashi Miwako, Momose Toshimitsu, Tanaka Shota, Takayanagi Shunsaku, Yanagisawa Shunsuke, Nejo Takahide, Takahashi Satoshi, Omata Mayu, Otani Ryohei, Saito Kuniaki, Narita Yoshitaka, Nagane Motoo, Nishikawa Ryo, Ueki Keisuke, Aburatani Hiroyuki, Saito Nobuhito

Abstract excerpt

Among diffuse gliomas, oligodendrogliomas show relatively better prognosis, respond well to radiotherapy and chemotherapy, and seldom progress to very aggressive tumors. To elucidate the genetic and epigenetic background for such behavior and tumor evolution during tumor relapse, we comparatively analyzed 12 pairs of primary and recurrent oligodendrogliomas with 1p/19q-codeletion. Initial treatment for these...

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Source

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Identifiers

PMID: 28270234
DOI: 10.1186/s40478-017-0422-z
PMCID: PMC5339990

Genes

CIC
IDH1
TCF12
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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