Article

TAPIR: a T-cell receptor language model for predicting rare and novel targets

2023-09-15

Abstract excerpt

T-cell receptors (TCRs) are involved in most human diseases, but linking their sequences with their targets remains an unsolved grand challenge in the field. In this study, we present TAPIR (T-cell receptor and Peptide Interaction Recognizer), a T-cell receptor (TCR) language model that predicts TCR-target interactions, with a focus on novel and rare targets. TAPIR employs deep convolutional neural network (CNN) e...

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Literature Corpus work: 25dd18fd-7fac-5cee-adc8-5fe060022231
DOI: 10.1101/2023.09.12.557285

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