Article

Split <i>Staphylococcus aureus</i> prime editor for AAV delivery

2021-01-11

Abstract excerpt

Prime editing brings immense promise to correct a large number of human pathogenic mutations and enact diverse edit types without introducing widespread undesired editing events. Delivery of prime editors in vivo would enable such edits to be introduced in a clinical setting. The coding sequence for prime editor, however, is too large to fit within the size-constrained adeno-associated virus (AAV) genome. Herein,...

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Literature Corpus work: 25c38c3d-f0b7-5900-b4aa-70a6a1c3d24a
DOI: 10.1101/2021.01.11.426237

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