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Analyzing long-read CRISPR experiments with CRISPRLungo

2025-10-21

Abstract excerpt

<h4>ABSTRACT</h4> Long-read sequencing can characterize complex genome editing-induced DNA sequence changes such as large deletions, insertions, and inversions that are difficult to detect using short-read sequencing. However, PCR amplification and sequencing errors complicate accurate variant detection, and existing analysis tools are not optimized for gene editing specific allelic outcomes. Here we present CRIS...

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Literature Corpus work: 25ba6113-bbe4-5e2c-846f-2cf029c0e8fb
DOI: 10.1101/2025.10.21.683786

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