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Article

Functional identification of cell phenotypes differentiating from mice retinal neurospheres using single cell calcium imaging.

Cellular and molecular neurobiology - 1 Aug 2011

De Melo Reis R A, Schitine C S, Köfalvi A, Grade S, Cortes L, Gardino P F, Malva J O, de Mello F G

Abstract excerpt

Degeneration of neural retina causes vision impairment and can lead to blindness. Neural stem and progenitor cells might be used as a tool directed to regenerative medicine of the retina. Here, we describe a novel platform for cell phenotype-specific drug discovery and screening of proneurogenic factors, able to boost differentiation of neural retinal progenitor cells. By using single cell calcium imaging (SCCI)...

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Source

Identifiers

PMID: 21409522
DOI: 10.1007/s10571-011-9673-6

Genes

BDNF
CNTF
GFAP
DCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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