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Reduced Folate Carrier 1 (RFC1/Slc19a1) Suppression Exacerbates Blood-Brain Barrier Breakdown in Experimental Ischemic Stroke in Adult Mice

2024-10-28

Abstract excerpt

<h4>ABSTRACT</h4> The Reduced Folate Carrier 1 (RFC1), also called solute carrier family 19 member 1 (SLC19A1/SLC19a1), is recognized for transporting folates across the blood-brain barrier (BBB). RFC1 has recently been defined as a hypoxia-immune related gene whose expression levels were induced by acute retinal ischemia, suggesting that RFC1 may have a role in the response of the brain to ischemic injury. Despi...

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Literature Corpus work: 24fb98e0-20d5-5449-90b9-9a3f2e59f9b7
DOI: 10.1101/2024.10.28.620539

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