Article
Rnf-213 knockout induces pericyte reduction and blood-brain barrier impairment in mouse
2023-02-02
Abstract excerpt
<title>Abstract</title> <p>Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by progressive occlusion of the internal carotid artery and the formation of an abnormal compensatory capillary network at the base of the brain. Genomics studies identified Ring finger protein 213 (RNF213) as a common genetic factor that increases the susceptibility to MMD in East Asian people. However, the functio...
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Identifiers and source
- Literature Corpus work
- 9dd48da2-4489-5a2e-a7db-5afa60c60de4
- DOI
- 10.21203/rs.3.rs-2526175/v1