Article
Transient middle cerebral artery occlusion in mice induces neuronal expression of RNF213, a susceptibility gene for moyamoya disease.
Brain research - 1 Jan 2016
Sato-Maeda Mika, Fujimura Miki, Kanoke Atsushi, Morita-Fujimura Yuiko, Niizuma Kuniyasu, Tominaga Teiji
Abstract excerpt
Although recent genome-wide and locus-specific association studies revealed that the RING finger protein 213 (RNF213) gene is an important susceptibility gene for moyamoya disease (MMD), the exact mechanism by which the genetic alteration of RNF213 contributes to the development of MMD has not yet been elucidated. A quantitative reverse transcription polymerase chain reaction (PCR) analysis revealed that the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
