Article

Reduced Folate Carrier 1 (RFC1/Slc19a1) Suppression Exacerbates Blood-Brain Barrier Breakdown in Experimental Ischemic Stroke in Adult Mice

2024-12-09

Abstract excerpt

<title>Abstract</title> The Reduced Folate Carrier 1 (RFC1), also called solute carrier family 19 member 1 (SLC19A1/SLC19a1), is recognized for transporting folates across the blood-brain barrier (BBB). RFC1 has recently been defined as a hypoxia-immune related gene whose expression levels were induced by acute retinal ischemia, suggesting that RFC1 may have a role in the response of the brain to ischemic inju...

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Literature Corpus work: da7fcc48-2a6f-597f-9dca-a6f710f232ac
DOI: 10.21203/rs.3.rs-5383891/v1

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