Article
The transcription factor ZNF469 regulates collagen production in liver fibrosis
2024-04-25
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) - characterized by excess accumulation of fat in the liver - now affects one third of the world’s population. As NAFLD progresses, extracellular matrix components including collagen accumulate in the liver causing tissue fibrosis, a major determinant of disease severity and mortality. To identify transcriptional regulators of fibrosis, we computationally inferred the activ...
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Identifiers and source
- Literature Corpus work
- 24cb9e26-1344-5a88-9bcc-aea6e7c03bbb
- DOI
- 10.1101/2024.04.25.591188