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LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosis

2025-01-18

Abstract excerpt

<h4>Summary</h4> Metabolic syndrome and excessive alcohol consumption result in liver injury and fibrosis, which is characterized by increased collagen production by activated Hepatic Stellate Cells (HSCs). LARP6, an RNA-binding protein, was shown to facilitate collagen production. However, LARP6 expression and functionality as a regulator of fibrosis development in a disease relevant model remains elusive. By us...

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Literature Corpus work
e424dbb5-ddde-5541-b349-2ca265686ad4
DOI
10.1101/2025.01.16.633226
Open publication

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LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosisDOI 10.1101/2025.01.16.633226
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