Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomics of Human Fibrotic Diseases: Disordered Wound Healing Response

14 Nov 2020

Abstract excerpt

Fibrotic disease, which is implicated in almost half of all deaths worldwide, is the result of an uncontrolled wound healing response to injury in which tissue is replaced by deposition of excess extracellular matrix, leading to fibrosis and loss of organ function. A plethora of genome-wide association studies, microarrays, exome sequencing studies, DNA methylation arrays, next-generation sequencing, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to IL-33, ST2, and ILC Pathways
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Systemic Sclerosis and Related Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33202590
DOI: 10.3390/ijms21228590

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomics of Human Fibrotic Diseases: Disordered Wound Healing ResponsePMID 33202590Read ↗

Shared and organ-specific gene expression programs of fibrotic diseasesSemantic proximity Read ↗

Profiling Fibrosis through Single-Cell and Spatial Transcriptomics Analysis: cell identity and tissue architectureSemantic proximity Read ↗

Shared and distinct mechanisms of fibrosis.Semantic proximity Read ↗

Epigenetic Modifications in Fibrotic Diseases: Implications for Pathogenesis and Pharmacological TargetsSemantic proximity Read ↗

Epigenetics and the overhealing wound: the role of DNA methylation in fibrosisSemantic proximity Read ↗

Spatial genomics: Mapping the landscape of fibrosisSemantic proximity Read ↗

Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe?Semantic proximity Read ↗

Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African AmericansSemantic proximity Read ↗

Cellular and molecular mechanisms in fibrosisSemantic proximity Read ↗

Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseasesSemantic proximity Read ↗

FibroDB: Expression Analysis of Protein-Coding and Long Non-Coding RNA Genes in FibrosisSemantic proximity Read ↗

Single-Cell RNA-Sequencing Identifies Bone Marrow-Derived Progenitor Cells as a Main Source of Extracellular Matrix-Producing Cells Across Multiple Organ-Based Fibrotic DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.