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Article

Focal adhesion kinase and p53 signal transduction pathways in cancer.

Frontiers in bioscience (Landmark edition) - 1 Jun 2010

Golubovskaya Vita M, Cance William

Abstract excerpt

Human cancer is characterized by a process of tumor cell motility, invasion, and metastasis. One of the critical tyrosine kinases that is linked to these processes of tumor invasion and survival is the Focal Adhesion Kinase (FAK). Our laboratory was the first to isolate FAK from human tumors, and...

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Share to Antineoplastic Agents
Share to Focal Adhesion Protein-Tyrosine Kinases
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms

Share to Promoter Regions, Genetic

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 20515733
DOI: 10.2741/3653
PMCID: PMC3136041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20515733-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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