Back to search

Article

An Integrated Pan-Cancer Analysis and Structure-Based Virtual Screening of GPR15

2019-07-23

Abstract excerpt

G protein-coupled receptor 15 (GPR15, also known as BOB) is an extensively studied orphan GPCR involving HIV infection, colonic inflammation and smoking-related diseases. Recently, GPR15 was deorphanized and its corresponding natural ligand demonstrated an ability of inhibiting cancer cell growth. However, no study reported the potential role of GPR15 in a pan-cancer manner. Using large-scale publicly available da...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
245c8bd0-4662-5d27-9855-b2edf6e34ee4
DOI
10.20944/preprints201907.0258.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
An Integrated Pan-Cancer Analysis and Structure-Based Virtual Screening of GPR15DOI 10.20944/preprints201907.0258.v1
An Integrated Pan-Cancer Analysis and Structure-Based Virtual Screening of GPR15.Semantic proximity
Emerging roles of a chemoattractant receptor GPR15 and ligands in pathophysiologySemantic proximity
Molecular recognition of the atypical chemokine-like peptide GPR15L by its cognate receptor GPR15Semantic proximity
Mapping growth differentiation factor-15 (GDF15)-mediated signaling pathways in cancer: insights into its role across different cancer typesSemantic proximity
The Orphan Receptor GPR151: Discovery, Expression, and Emerging Biological SignificanceSemantic proximity
A Multi-Omics Analysis of the Prognostic Biomarker GDF15 Associated with Immune Infiltration and Regulated Mitochondrial-Dependent Apoptosis in Colorectal CancerSemantic proximity
A Pan-cancer analysis of GPR183 correlated with tumor immunitySemantic proximity
The emerging roles of GPRC5A in diseasesSemantic proximity
Activation of GPR15 and its involvement in the biological effects of smokingSemantic proximity
Origin of the GPR15LG–GPR15 signaling axis in ancient fish ancestorsSemantic proximity
GPRC5A: An Emerging Biomarker in Human CancerSemantic proximity
GPR65 as a potential immune checkpoint regulates the immune microenvironment according to pan-cancer analysisSemantic proximity
Select a neighboring publication to make it the new centre.