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GPR65 as a potential immune checkpoint regulates the immune microenvironment according to pan-cancer analysis

1 Feb 2023

Abstract excerpt

It has been reported that inhibition of GPR65 may be effective for the treatment of certain cancers. Nevertheless, the role of GPR65 in various cancers remains unknown. We conducted an exhaustive pan-cancer analysis of GPR65 using multiple databases, including TCGA, GTEx, BioGPS, HPA, cBioPortal, and GeneCards. GPR65 was found to be differentially expressed in various cancers and linked to tumor mutational burden...

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PMID: 36852075
DOI: 10.1016/j.heliyon.2023.e13617

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