Article
An Integrated Pan-Cancer Analysis and Structure-Based Virtual Screening of GPR15.
International journal of molecular sciences - 10 Dec 2019
Wang Yanjing, Wang Xiangeng, Xiong Yi, Li Cheng-Dong, Xu Qin, Shen Lu, Chandra Kaushik Aman, Wei Dong-Qing
Abstract excerpt
G protein-coupled receptor 15 (GPR15, also known as BOB) is an extensively studied orphan G protein-coupled receptors (GPCRs) involving human immunodeficiency virus (HIV) infection, colonic inflammation, and smoking-related diseases. Recently, GPR15 was deorphanized and its corresponding natural ligand demonstrated an ability to inhibit cancer cell growth. However, no study reported the potential role of GPR15 in...
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