Article

Echidna: integrated simulations of single-cell immune receptor repertoires and transcriptomes

2021-07-19

Abstract excerpt

Single-cell sequencing now enables the recovery of full-length immune repertoires [B cell receptor (BCR) and T cell receptor (TCR) repertoires], in addition to gene expression information. The feature-rich datasets produced from such experiments require extensive and diverse computational analyses, each of which can significantly influence the downstream immunological interpretations, such as clonal selection and...

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Literature Corpus work: 24543c19-0a26-5d93-b7ef-a5149665408e
DOI: 10.1101/2021.07.17.452792

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