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Hyaluronidase isoforms can promote or suppress glioma invasion within 3D Hyaluronic Acid Matrices

2026-08-10

Abstract excerpt

<h4>ABSTRACT</h4> Glioblastoma (GBM) is defined by infiltration of tumor cells throughout the brain, which drives resistance, recurrence and mortality. Although cell-derived hyaluronidases (HYALs) have been collectively implicated in invasion-associated matrix digestion, we were motivated to investigate contributions of specific HYAL isoforms, which execute a diversity of cell-autonomous and matrix-based function...

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Literature Corpus work
2440ec14-4fd6-5059-8869-d4b96f4d9b2b
DOI
10.64898/2026.08.07.743533
Open publication

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Hyaluronidase isoforms can promote or suppress glioma invasion within 3D Hyaluronic Acid MatricesDOI 10.64898/2026.08.07.743533
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