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Dissecting TGF-β-induced glioblastoma invasion with engineered hyaluronic acid hydrogels

1 Jun 2024

Abstract excerpt

Glioma stem cells (GSCs) contribute to rapid cellular invasion in glioblastoma (GBM). Transforming growth factor-β (TGF-β) has been strongly implicated in supporting key GSC functions, including stemness, immunosuppression, and resistance. Although TGF-β is well-known as a driver of cancer invasion, how TGF-β supports the invasion of GSCs is not well understood. Progress in understanding mechanisms of...

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PMID: 38894960
DOI: 10.1063/5.0203213

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