Article

CRTAC1-A reprograms extracellular matrix viscoelasticity to constrain glioma progression

2026-05-09

Abstract excerpt

Mechanical remodeling of the extracellular matrix (ECM) influences glioma progression, yet the molecular regulators that control tumor matrix mechanics remain poorly understood. By comparing low-grade gliomas (LGGs), associated with improved patient survival, with glioblastomas (GBMs), which carry a poor prognosis, we identified the cartilage-derived ECM protein CRTAC1-A as enriched in LGGs and significantly reduc...

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Literature Corpus work: abeaf2af-4bdd-5c68-845f-52cf531ba0df
DOI: 10.64898/2026.05.06.723198

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