Article

Targeting Scavenger Receptor Type B1 In Cholesterol-Addicted Lymphomas Abolishes Glutathione Peroxidase 4 and Results in Ferroptosis

2020-06-17

Abstract excerpt

<h4>ABSTRACT</h4> Normal human cells can either synthesize or uptake cholesterol from lipoproteins to meet their metabolic requirements. Some malignant cells absolutely require cholesterol uptake from lipoproteins for survival because de novo cholesterol synthesis genes are transcriptionally silent or mutated. Recent data suggest that lymphoma cells dependent upon lipoprotein-mediated cholesterol uptake are also...

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Literature Corpus work: 242ca03c-7829-554a-8575-4856d6261e8f
DOI: 10.1101/2020.06.16.155242

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Targeting Scavenger Receptor Type B1 In Cholesterol-Addicted Lymphomas Abolishes Glutathione Peroxidase 4 and Results in FerroptosisDOI 10.1101/2020.06.16.155242Read

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