Article
Ca <sup>2+</sup> /Calmodulin Dependent Protein Kinase Kinase-2 (CaMKK2) promotes Protein Kinase G (PKG)-dependent actin cytoskeletal assembly to increase tumor metastasis
2023-04-18
Abstract excerpt
Triple-negative breast cancers (TNBCs) tend to become highly invasive early during cancer development. Despite some successes in the initial treatment of patients diagnosed with early-stage localized TNBC, the rate of metastatic recurrence remains high with poor long-term survival outcomes. Here we show that elevated expression of the serine/threonine-kinase, Calcium/Calmodulin (CaM)-dependent protein kinase kinas...
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Identifiers and source
- Literature Corpus work
- 2411cf70-6811-5757-b7e2-c0cba4e9d95a
- DOI
- 10.1101/2023.04.17.536051
