Article

CACNA1C as a Prognostic Biomarker and Therapeutic Target in High-Grade Serous Ovari-an Cancer: Clinical Validation and Molecular Dynamics of Nifedipine Blockade

2026-04-22

Abstract excerpt

High-Grade Serous Ovarian Cancer (HGSOC) is the most lethal gynecological malignancy due to aggressive growth, widespread metastases, and high intra-tumoral heterogeneity. Poor prognosis is largely due to late diagnosis, hence there is an urgent need to identify novel biomarkers for screening, diagnosis, and monitoring. Here, we propose the voltage-dependent calcium channel hCaV1.2 encoded by CACNA1C as a potentia...

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Literature Corpus work: f63fc17d-3bed-57eb-a10c-abd1a01cb954
DOI: 10.64898/2026.04.19.719516

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