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CAMK1D amplification implicated in epithelial–mesenchymal transition in basal‐like breast cancer

2 Oct 2008

Abstract excerpt

Breast cancer exhibits clinical and molecular heterogeneity, where expression profiling studies have identified five major molecular subtypes. The basal-like subtype, expressing basal epithelial markers and negative for estrogen receptor (ER), progesterone receptor (PR) and HER2, is associated with higher overall levels of DNA copy number alteration (CNA), specific CNAs (like gain on chromosome 10p), and poor...

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PMID: 19383354
DOI: 10.1016/j.molonc.2008.09.004

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