Article

Focal cortical dysplasia type II-dependent maladaptive myelination in the human frontal lobe

2024-03-06

Abstract excerpt

Focal cortical dysplasias (FCDs) are local malformations of the human neocortex and a leading cause of intractable epilepsy. FCDs are classified into different subtypes including FCD IIa and IIb, characterized by a blurred gray-white matter boundary or a transmantle sign indicating abnormal white matter myelination. Recently, we have shown that myelination is also compromised in the gray matter of FCD IIa of the t...

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Literature Corpus work: 240a8bac-d109-5501-8e67-e315d746d754
DOI: 10.1101/2024.03.02.582894

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