Article

Transcriptome analyses of the cortex and white matter of focal cortical dysplasia type II: insights into disease mechanisms and tissue characterization

2022-08-25

Abstract excerpt

<h4>ABSTRACT</h4> Focal cortical dysplasia (FCD) is a common cause of pharmacoresistant epilepsy. According to the 2022 International League Against Epilepsy classification, FCD type II is characterized by dysmorphic neurons (IIa and IIb) and may be associated with balloon cells (IIb). We present a multicentric study to evaluate the transcriptomes of the gray and white matters of surgical FCD type II specimens. We...

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Literature Corpus work: 00eb0c1e-b3e6-5dec-88b7-9295586b10e2
DOI: 10.1101/2022.08.23.22279011

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