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Focal cortical dysplasia type II: review of neuropathological manifestations and pathogenetic mechanisms

17 Feb 2025

Abstract excerpt

Focal cortical dysplasia (FCD) is an important cause of intractable epilepsy, with FCD type II (FCD II) being the most common subtype. FCD II is characterized by cortical dyslamination accompanied by dysmorphic neurons (DNs). Identifying the molecular alterations and targetable biomarkers is pivotal for developing therapies. Here, we provide a detailed description of the neuropathological manifestations of FCD...

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PMID: 40217346
DOI: 10.1186/s42494-024-00195-y

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