Article
Assessing the clinical utility of cancer genomic and proteomic data across tumor types.
Nature biotechnology - 1 Jul 2014
Yuan Yuan, Van Allen Eliezer M, Omberg Larsson, Wagle Nikhil, Amin-Mansour Ali, Sokolov Artem, Byers Lauren A, Xu Yanxun, Hess Kenneth R, Diao Lixia, Han Leng, Huang Xuelin, Lawrence Michael S, Weinstein John N, Stuart Josh M, Mills Gordon B, Garraway Levi A, Margolin Adam A, Getz Gad, Liang Han
Abstract excerpt
Molecular profiling of tumors promises to advance the clinical management of cancer, but the benefits of integrating molecular data with traditional clinical variables have not been systematically studied. Here we retrospectively predict patient survival using diverse molecular data (somatic copy-number alteration, DNA methylation and mRNA, microRNA and protein expression) from 953 samples of four cancer types...
Topics
Join the communities discussing this publication.